Francesca Eastwood attends HFPA and InStyle's Golden Globe award season celebration at Cecconi's on Thursday, Nov. 29, 2012, in West Hollywood. (Photo by Katy Winn/Invision/AP)
Francesca Eastwood attends HFPA and InStyle's Golden Globe award season celebration at Cecconi's on Thursday, Nov. 29, 2012, in West Hollywood. (Photo by Katy Winn/Invision/AP)
Frances Fisher, at left, and Francesca Eastwood attends HFPA and InStyle's Golden Globe award season celebration at Cecconi's on Thursday, Nov. 29, 2012, in West Hollywood, Calif. (Photo by Katy Winn/Invision/AP)
Gia Montegna, from left, Francesca Eastwood, and Dr. Aida Takla-O'Reilly attend HFPA and InStyle's Golden Globe award season celebration at Cecconi's on Thursday, Nov. 29, 2012, in West Hollywood, Calif. (Photo by Katy Winn/Invision/AP)
WEST HOLLYWOOD, Calif. (AP) ? The Hollywood Foreign Press Association has named its newest Miss Golden Globe.
Francesca Eastwood was introduced as the 2013 honoree Thursday at Cecconi's restaurant in West Hollywood. The 19-year-old is the daughter of Hollywood icon Clint Eastwood.
Miss Golden Globe is traditionally the child of a celebrity who is invited to help during the ceremony. Previous honorees include Rumer Willis, Laura Dern, Melanie Griffith and Joely Fisher.
Francesca Eastwood is an actress who also stars with her stepmother, Dina Eastwood, her half-sister, Morgan Eastwood, and the South African boy band Overtone in the E! reality series "Mrs. Eastwood and Company." She's currently enrolled at the University of Southern California.
Nominations for the 70th annual Golden Globe Awards will be announced Dec. 13. The ceremony is set for Jan. 13.
Jackman joins original 'X-Men' players Patrick Stewart and Ian McKellen for Singer's return to the franchise. But will he steal the show? By Josh Wigler
Hugh Jackman in "X-Men Origins: Wolverine" Photo: Fox
Automotive ArtDiscuss Classic Automobile Dealer Service Signs #2 in the AACA GENERAL DISCUSSION forums; I'm not sure how many signs I can post here for you but I'll keep posting until they tell me to stop. Think I'll try them alphabetically. Fred Melbourne FL...
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After the success of Louis CK's direct-to-fan specials, video startup Chill is pivoting -- again -- and coming out with a new product that it hopes will provide a new channel for independent content creators to sell their videos in the same fashion.
A human-caused climate change signal emerges from the noisePublic release date: 29-Nov-2012 [ | E-mail | Share ]
Contact: Anne Stark stark8@llnl.gov 925-422-9799 DOE/Lawrence Livermore National Laboratory
Livermore, Calif. -- By comparing simulations from 20 different computer models to satellite observations, Lawrence Livermore climate scientists and colleagues from 16 other organizations have found that tropospheric and stratospheric temperature changes are clearly related to human activities.
The team looked at geographical patterns of atmospheric temperature change over the period of satellite observations. The team's goal of the study was to determine whether previous findings of a "discernible human influence" on tropospheric and stratospheric temperature were sensitive to current uncertainties in climate models and satellite data.
The troposphere is the lowest portion of earth's atmosphere. The stratosphere sits just above the troposphere, between 6 and 30 miles above earth's surface.
The satellite temperature data sets were produced by three different research groups, and rely on measurements of the microwave emissions of oxygen molecules. Each group made different choices in processing these raw measurements, and in accounting for such complex effects as drifts in satellite orbits and in instrument calibrations.
The new climate model simulations analyzed by the team will form the scientific backbone of the upcoming 5th assessment of the Intergovernmental Panel on Climate Change, which is due out in 2014.
In both satellite observations and the computer model simulations of historical climate change, the lower stratosphere cools markedly over the past 33 years. This cooling is primarily a response to the human-caused depletion of stratospheric ozone. The observations and model simulations also show a common pattern of large-scale warming of the lower troposphere, with largest warming over the Arctic, and muted warming (or even cooling) over Antarctica. Tropospheric warming is mainly driven by human-caused increases in well-mixed greenhouse gases.
"It's very unlikely that purely natural causes can explain these distinctive patterns of temperature change," said Laboratory atmospheric scientist Benjamin Santer, who is lead author of the paper appearing in the Nov. 29 online edition of the journal, Proceedings of the National Academy of Sciences. "No known mode of natural climate variability can cause sustained, global-scale warming of the troposphere and cooling of the lower stratosphere."
The team analyzed results from climate model simulations with specified historical changes in human and natural external factors, and from simulations with projected 21st century changes in greenhouse gases and anthropogenic aerosols. They also looked at simulations with no changes in external influences on climate, which provide information on the year-to-year and decade-to-decade "noise" of internal climate variability, arising from such natural phenomena as the El Nio/Southern Oscillation and the Pacific Decadal Oscillation.
The team used a standard "climate fingerprint" method to search for the model signal pattern (in response to human influences, the sun and volcanoes) in the satellite observations. The method quantifies the strength of the signal in observations, relative to the strength of the signal in natural climate noise.
###
Other contributors include researchers from Remote Sensing Systems of Santa Rosa; the Centre for Australian Weather and Climate Research, Melbourne, Australia; the Canadian Centre for Climate Modeling and Analysis, Victoria, Canada; the National Oceanic and Atmospheric Administration (NOAA) Geophysical Fluid Dynamics Laboratory, Princeton; the University of Colorado, Boulder; the Massachusetts Institute of Technology, Cambridge; the U.K. Met. Office Hadley Centre, Exeter, U.K.; the Centre National de la Recherche Scientifique, Toulouse, France; North Carolina State University; the National Climatic Data Center, Asheville; Lawrence Berkeley National Laboratory; the National Center for Atmospheric Research, Boulder; the University of Adelaide, South Australia; the University of Reading, U.K.; and the Center for Satellite Applications and Research, Camp Springs. The paper is Santer's inaugural article as a member of the U.S. National Academy of Sciences.
Founded in 1952, Lawrence Livermore National Laboratory provides solutions to our nation's most important national security challenges through innovative science, engineering and technology. Lawrence Livermore National Laboratory is managed by Lawrence Livermore National Security, LLC for the U.S. Department of Energy's National Nuclear Security Administration.
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A human-caused climate change signal emerges from the noisePublic release date: 29-Nov-2012 [ | E-mail | Share ]
Contact: Anne Stark stark8@llnl.gov 925-422-9799 DOE/Lawrence Livermore National Laboratory
Livermore, Calif. -- By comparing simulations from 20 different computer models to satellite observations, Lawrence Livermore climate scientists and colleagues from 16 other organizations have found that tropospheric and stratospheric temperature changes are clearly related to human activities.
The team looked at geographical patterns of atmospheric temperature change over the period of satellite observations. The team's goal of the study was to determine whether previous findings of a "discernible human influence" on tropospheric and stratospheric temperature were sensitive to current uncertainties in climate models and satellite data.
The troposphere is the lowest portion of earth's atmosphere. The stratosphere sits just above the troposphere, between 6 and 30 miles above earth's surface.
The satellite temperature data sets were produced by three different research groups, and rely on measurements of the microwave emissions of oxygen molecules. Each group made different choices in processing these raw measurements, and in accounting for such complex effects as drifts in satellite orbits and in instrument calibrations.
The new climate model simulations analyzed by the team will form the scientific backbone of the upcoming 5th assessment of the Intergovernmental Panel on Climate Change, which is due out in 2014.
In both satellite observations and the computer model simulations of historical climate change, the lower stratosphere cools markedly over the past 33 years. This cooling is primarily a response to the human-caused depletion of stratospheric ozone. The observations and model simulations also show a common pattern of large-scale warming of the lower troposphere, with largest warming over the Arctic, and muted warming (or even cooling) over Antarctica. Tropospheric warming is mainly driven by human-caused increases in well-mixed greenhouse gases.
"It's very unlikely that purely natural causes can explain these distinctive patterns of temperature change," said Laboratory atmospheric scientist Benjamin Santer, who is lead author of the paper appearing in the Nov. 29 online edition of the journal, Proceedings of the National Academy of Sciences. "No known mode of natural climate variability can cause sustained, global-scale warming of the troposphere and cooling of the lower stratosphere."
The team analyzed results from climate model simulations with specified historical changes in human and natural external factors, and from simulations with projected 21st century changes in greenhouse gases and anthropogenic aerosols. They also looked at simulations with no changes in external influences on climate, which provide information on the year-to-year and decade-to-decade "noise" of internal climate variability, arising from such natural phenomena as the El Nio/Southern Oscillation and the Pacific Decadal Oscillation.
The team used a standard "climate fingerprint" method to search for the model signal pattern (in response to human influences, the sun and volcanoes) in the satellite observations. The method quantifies the strength of the signal in observations, relative to the strength of the signal in natural climate noise.
###
Other contributors include researchers from Remote Sensing Systems of Santa Rosa; the Centre for Australian Weather and Climate Research, Melbourne, Australia; the Canadian Centre for Climate Modeling and Analysis, Victoria, Canada; the National Oceanic and Atmospheric Administration (NOAA) Geophysical Fluid Dynamics Laboratory, Princeton; the University of Colorado, Boulder; the Massachusetts Institute of Technology, Cambridge; the U.K. Met. Office Hadley Centre, Exeter, U.K.; the Centre National de la Recherche Scientifique, Toulouse, France; North Carolina State University; the National Climatic Data Center, Asheville; Lawrence Berkeley National Laboratory; the National Center for Atmospheric Research, Boulder; the University of Adelaide, South Australia; the University of Reading, U.K.; and the Center for Satellite Applications and Research, Camp Springs. The paper is Santer's inaugural article as a member of the U.S. National Academy of Sciences.
Founded in 1952, Lawrence Livermore National Laboratory provides solutions to our nation's most important national security challenges through innovative science, engineering and technology. Lawrence Livermore National Laboratory is managed by Lawrence Livermore National Security, LLC for the U.S. Department of Energy's National Nuclear Security Administration.
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Protein injection points to muscular dystrophy treatmentPublic release date: 27-Nov-2012 [ | E-mail | Share ]
Contact: Paddy Moore padmoore@ohri.ca 613-737-8899 x73687 Ottawa Hospital Research Institute
November 27, 2012 Ottawa Scientists have discovered that injecting a novel human protein into muscle affected by Duchenne muscular dystrophy significantly increases its size and strength, findings that could lead to a therapy akin to the use of insulin by diabetics. These results were published today in the Proceedings of the National Academy of Sciences by Dr. Julia von Maltzahn and Dr. Michael Rudnicki, the Ottawa scientist who discovered muscle stem cells in adults.
"This is an unprecedented and dramatic restoration in muscle strength," says Dr. Rudnicki, a senior scientist and director for the Regenerative Medicine Program and Sprott Centre for Stem Cell Research at the Ottawa Hospital Research Institute. He is also a Canada Research Chair in Molecular Genetics and professor in the Faculty of Medicine at the University of Ottawa.
"We know from our previous work that this protein, called Wnt7a, promotes the growth and repair of healthy muscle tissue. In this study we show the same types of improvement in a mouse model of Duchenne muscular dystrophy. We found that Wnt7a injections increased muscle strength almost two-fold, to nearly normal levels. We also found that the size of the muscle fibre increased and there was less muscle damage, compared to mice not given Wnt7a."
Duchenne muscular dystrophy is a genetic disorder that affects one of every 3,500 newborn males. In Canada, all types of muscular dystrophy affect more than 50,000 people. The disease often progresses to a state where the muscles are so depleted that the person dies due to an inability to breath. For people with Duchenne muscular dystrophy, this usually happens in their 20s or 30s.
"This is also exciting because we think it's a therapeutic approach that could apply to other muscle-wasting diseases," says Dr. Rudnicki.
Dr. Rudnicki's lab is a world leader in research on muscle stem cells. They have contributed significantly to our understanding of how these cells work at the molecular level. This basic research, which takes place in OHRI's multidisciplinary environment of collaboration with clinicians, led to the identification of Wnt7a as a promising candidate to help people with this muscle wasting disease.
Biotechnology partner, Fate Therapeutics is currently developing Wnt7a-based therapeutic candidates for treatment of muscular dystrophy and atrophy. Preclinical assessments are ongoing and the company plans to initiate clinical trials in the near future.
###
The full article, "Wnt7a treatment ameliorates muscular dystrophy," is available online ahead of print through the Proceedings of the National Academy of Sciences site.
This research was supported by the Muscular Dystrophy Association, the Ontario Ministry of Economic Development and Innovation, the Canadian Institutes of Health Research, the National Institutes of Health, the Howard Hughes Medical Institute, Fate Therapeutics and the Canada Research Chair Program. All research at OHRI is also supported by The Ottawa Hospital Foundation.
Media Contact
Paddy Moore
Manager, Communications and Public Relations,
Ottawa Hospital Research Institute
613-798-5555 ext. 73687
613-794-6912 (cell)
padmoore@ohri.ca
Nomie Duval
Media Relations Officer
University of Ottawa
613-562-5800 x2981
613-863-7221 (cell)
neomie.duval@uOttawa.ca
About the Ottawa Hospital Research Institute (OHRI)
The Ottawa Hospital Research Institute (OHRI) is the research arm of The Ottawa Hospital and is an affiliated institute of the University of Ottawa, closely associated with the university's Faculties of Medicine and Health Sciences. OHRI includes more than 1,700 scientists, clinical investigators, graduate students, postdoctoral fellows and staff conducting research to improve the understanding, prevention, diagnosis and treatment of human disease. Research at OHRI is supported by The Ottawa Hospital Foundation. www.ohri.ca
About the University of Ottawa
The University of Ottawa is committed to research excellence and encourages an interdisciplinary approach to knowledge creation, which attracts the best academic talent from across Canada and around the world. It is an important stakeholder in the National Capital Region's economic development.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Protein injection points to muscular dystrophy treatmentPublic release date: 27-Nov-2012 [ | E-mail | Share ]
Contact: Paddy Moore padmoore@ohri.ca 613-737-8899 x73687 Ottawa Hospital Research Institute
November 27, 2012 Ottawa Scientists have discovered that injecting a novel human protein into muscle affected by Duchenne muscular dystrophy significantly increases its size and strength, findings that could lead to a therapy akin to the use of insulin by diabetics. These results were published today in the Proceedings of the National Academy of Sciences by Dr. Julia von Maltzahn and Dr. Michael Rudnicki, the Ottawa scientist who discovered muscle stem cells in adults.
"This is an unprecedented and dramatic restoration in muscle strength," says Dr. Rudnicki, a senior scientist and director for the Regenerative Medicine Program and Sprott Centre for Stem Cell Research at the Ottawa Hospital Research Institute. He is also a Canada Research Chair in Molecular Genetics and professor in the Faculty of Medicine at the University of Ottawa.
"We know from our previous work that this protein, called Wnt7a, promotes the growth and repair of healthy muscle tissue. In this study we show the same types of improvement in a mouse model of Duchenne muscular dystrophy. We found that Wnt7a injections increased muscle strength almost two-fold, to nearly normal levels. We also found that the size of the muscle fibre increased and there was less muscle damage, compared to mice not given Wnt7a."
Duchenne muscular dystrophy is a genetic disorder that affects one of every 3,500 newborn males. In Canada, all types of muscular dystrophy affect more than 50,000 people. The disease often progresses to a state where the muscles are so depleted that the person dies due to an inability to breath. For people with Duchenne muscular dystrophy, this usually happens in their 20s or 30s.
"This is also exciting because we think it's a therapeutic approach that could apply to other muscle-wasting diseases," says Dr. Rudnicki.
Dr. Rudnicki's lab is a world leader in research on muscle stem cells. They have contributed significantly to our understanding of how these cells work at the molecular level. This basic research, which takes place in OHRI's multidisciplinary environment of collaboration with clinicians, led to the identification of Wnt7a as a promising candidate to help people with this muscle wasting disease.
Biotechnology partner, Fate Therapeutics is currently developing Wnt7a-based therapeutic candidates for treatment of muscular dystrophy and atrophy. Preclinical assessments are ongoing and the company plans to initiate clinical trials in the near future.
###
The full article, "Wnt7a treatment ameliorates muscular dystrophy," is available online ahead of print through the Proceedings of the National Academy of Sciences site.
This research was supported by the Muscular Dystrophy Association, the Ontario Ministry of Economic Development and Innovation, the Canadian Institutes of Health Research, the National Institutes of Health, the Howard Hughes Medical Institute, Fate Therapeutics and the Canada Research Chair Program. All research at OHRI is also supported by The Ottawa Hospital Foundation.
Media Contact
Paddy Moore
Manager, Communications and Public Relations,
Ottawa Hospital Research Institute
613-798-5555 ext. 73687
613-794-6912 (cell)
padmoore@ohri.ca
Nomie Duval
Media Relations Officer
University of Ottawa
613-562-5800 x2981
613-863-7221 (cell)
neomie.duval@uOttawa.ca
About the Ottawa Hospital Research Institute (OHRI)
The Ottawa Hospital Research Institute (OHRI) is the research arm of The Ottawa Hospital and is an affiliated institute of the University of Ottawa, closely associated with the university's Faculties of Medicine and Health Sciences. OHRI includes more than 1,700 scientists, clinical investigators, graduate students, postdoctoral fellows and staff conducting research to improve the understanding, prevention, diagnosis and treatment of human disease. Research at OHRI is supported by The Ottawa Hospital Foundation. www.ohri.ca
About the University of Ottawa
The University of Ottawa is committed to research excellence and encourages an interdisciplinary approach to knowledge creation, which attracts the best academic talent from across Canada and around the world. It is an important stakeholder in the National Capital Region's economic development.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
The Minnesota DNR provided the following summaries of last week's activities by Conservation Officers:
CO Brad Schultz (Cook) reports working on some leftover items from the rifle deer season and the first wolf hunting season. The bays of area lakes have frozen over with very thin ice.? Please don?t put your life, and the lives of the first responders, at risk by going out on this dangerous ice. Also, keep a close watch on the kids and pets and keep them away from the thin ice.
CO Troy Fondie (Orr) reports monitoring forest roads, snowmobile activity has been observed, public access sites continue to be monitored. Lakes have frozen.
CO Dan Starr (Tower) finished up some deer season issues and marked some baited stands to visit next year. A wolf season case continues to be investigated. Trapping and muzzleloading season started with a few deer around, but mostly moving at night. Snow and cold are welcome by some, but dreaded by others who stayed inside. A meeting was held with the county attorney to resolve a pending DUI case and upcoming jury trial. Some hare hunters were checked, but fresh snow made the white critters hard to see.
CO Don Bozovsky (Hibbing) followed up on cases from the rifle deer season and worked muzzleloader, wolf, fisher and marten openers. A trespass follow up revealed violations of trespassing, driving after revocation, fail to validate site tag and fail to register deer. A deer hunting complaint that involved a felon in possession of a firearm and a number of deer hunting violations was worked and is nearly readied for charges. The saga of dumped deer carcasses continues. An individual hunting grouse without adequate blaze orange admitted to illegally dumping pieces of his processed deer into the river. While dealing with that issue, the officer found an illegally set trap from another individual. Enforcement action was taken.
CO Matt Frericks (Virginia) spent time preparing reports to be turned into court stemming from big game violations. More follow up into other violations that occurred during the deer season are still ongoing. An alarming number of deer carcasses have started to be found in road ditches throughout the Virginia area. CO Frericks would like to remind people that not only is this littering but it also gives hunters and sportsmen a poor image. CO Frericks advises that people dispose of their deer carcasses by taking them to a local landfill and spending a dollar or two instead of risking a $185 fine. ?
CO Mark Fredin (Aurora) received numerous calls from outraged people on three deer carcasses dumped in a ditch by Bass Lake. Two of the deer had heads removed. The third was a doe only partially processed leaving back straps and hindquarters unprocessed. Other hind quarters were discarded off to the side unprocessed. CO Fredin while doing a routine check of hunters in deer stands found one to be hunting without a license and the other to be hunting on an invalid license due to purchasing the license during the season and not waiting he required two days before hunting. Thanks to fresh snow many traps were check for fisher/marten/wolf seasons.?? ?
CO John Velsvaag (Ely) checked up on several deer baiting complaints this past week. CO Velsvaag took several calls on the upcoming second wolf season. He also followed up on complaints of early pine marten trapping.
CO Marty Stage (Ely) worked on cases that were left over from the deer season. Time was spent putting away boats since the lakes are frozen up now. The second wave of hunters has shown up for wolf, muzzleloader, and marten and fisher trapping. Trappers are reminded that if they don?t want the conservation officer to alter their sets any more than is absolutely necessary, they should not roll their ID tags into a little ball. Doing this makes the tag difficult to read.
CO Anthony Bermel (Babbitt / Ely) reports the first snowstorm of the year and ice forming on the lakes, bringing winter sports here soon. An investigation from deer season was completed with enforcement action taken for hunting deer without a license and a rifle was seized. Whitefish netting was monitored. A busy wolf, muzzleloader deer, and fisher/marten opener was worked. Other enforcement action for the week included over limit of crappies, unregistered ATV, trespass, commercial records violation, fail to register deer, transport loaded gun in motor vehicle, no blaze orange while trapping, fail to validate marten site coupon, set trap on pole with illegal diameter, and no trapping license in possession.
CO Sarah Sindelir (Grand Rapids) spent time this past week working on follow-up complaints from deer season. She also taught snowmobile laws at a snowmobile safety class. She took several questions concerning the muzzle loader season.
CO Shawn Wichmann (Hill City) worked post firearms deer season investigations. Enforcement action was taken on an individual taking a deer during closed season with artificial light and bait. Wichmann also checked the area for trapping activity.
CO Jayson Hansen (Bigfork) worked small game, trapping and started field training work with COC Belgard. Violations of trespass and ATV?s on the roadway were encountered.
CO Randy Patten (Northome) checked trappers and muzzleloader hunters and continued to work on investigations from the rifle deer season.
CO Thomas Sutherland (Grand Rapids) worked trapping activity the last week with multiple furbearer seasons opening over the weekend. CO Sutherland also finished up work from the regular firearms deer season and started work on muzzleloader deer season.
CO Mike Fairbanks (Deer River) worked with COC Belgard. They checked small game and deer and wolf hunters/trappers. Enforcement contacts were made for a small game license violation and a wolf trapping violation.
CO Andy Schmidt (Brookston) completed investigations from the firearm deer season. Deer carcass dumping complaints continue after the season.
CO Jeff Birchem (Baudette) continued to follow up on cases from the firearms season. Area trappers were checked and CO Birchem also assisted young trappers from the Baudette school. Muzzleloader hunters were checked on the opening weekend. Ice conditions are very poor in the bays and extreme caution should be used. ?
CO Robert Gorecki (Baudette) monitored early ice fishing, muzzleloading, and trapping activity throughout the week. A few early ice anglers were checked on Upper Red Lake, but ice conditions are inconsistent and vary greatly. Caution should be used. CO Gorecki assisted CO Birchem in a trapping field exercise, and muzzleloader hunters were checked during the week. ?
CO Keith Backer (Blackduck) checked muzzleloader hunters and several trappers. Ice on area lakes will require much additional cold weather before safe for foot travel.
CO Brice Vollbrecht (Bemidji) conducted follow up investigations from the firearm deer season. A district meeting and training was attended at Itasca State Park. CO Vollbrecht worked with the area Local Gov?t Unit (LGU) on wetland violations.
CO Gary Sommers (Walker) reports primary enforcement efforts this past week focused on big and small game hunting, and trapping activity.
CO Mark Mathy (Cass Lake) checked muzzleloader deer hunters, trapping activity, and late season wolf hunters. He received calls about an injured owl, wolf law questions, and an injured goose. Officer Mathy also continued to work on cases initiated during the firearms deer season.
CO Larry Francis (Remer) continued to follow-up on cases from deer season. He put equipment into storage and prepared his snowmobile for use. Winter is here; lakes are freezing and the snow is falling. This past weekend brought out quite a few muzzleloader hunters; compliance with regulations was good. ?
CO Duke Broughten (Longville) spent the week monitoring hunting and trapping activity.? Muzzleloader deer season is off to a slow start with few hunters observed over the weekend. CO Broughten continued to receive calls concerning the dumping of deer carcasses and also followed up on cases from the firearms deer season. ?
The Xerox DocuMate 4830 ($2,495 direct) isn't just more expensive than most desktop document scanners. It's different too. First, it offers both an automatic document feeder (ADF) and a flatbed, so you can scan bound pages and originals you don't want to risk damaging. And second, both the flatbed and ADF are big enough to handle cut sheets up to U.S. tabloid size (11 by 17 inches) or ISO A3 size (11.69 by 16.54 inches). Not everyone needs to scan at these large sizes. But for those who do, the combination of the large format, a flatbed, and an ADF make the 4830 well worth the price.
You can find less expensive large-format scanners, although there aren't a lot of them. The Plustek OpticPro A320 ($599 street, 3 stars) comes to mind, for example. However, the Plustek A320 doesn't have an ADF, and for most document scanning, an ADF is a must-have convenience that can easily pay for itself in time saved. Beyond that, the ADFs on some scanners, including the 4830, will let you scan far larger sheets of paper than can fit on the flatbed.
The maximum paper size for the 4830 is 11.69 by 118 inches. (At least, that's what the spec sheet says. I didn?t have any paper that long to test with.) However, it's also worth noting that the flatbed cheats a little on size by being not quite big enough for a full tabloid-size sheet (or ledger-size sheet, which is the same size in landscape orientation). I measured the platen at 12 inches by just a little short of 17 inches, which means you can't quite scan a tabloid-size page edge to edge. This shouldn't be a problem with documents, however, since virtually any document will have at least a small margin.
Setup and Scanning Aside from needing more than the usual amount of flat space for the 7.6 by 22.9 by 19.6 inch 4830, setup is standard fare. Put the scanner in place, unlock it, connect a USB cable, and run the installation program.
In addition to a scan utility, the 4830 comes with two application programs: Nuance OmniPage Professional 17 for optical character recognition (OCR) and Nuance PDF Converter Professional 7 for managing PDF files. Both are excellent programs and are good choices for document scanning needs. However, the installation program also installs Twain, ISIS, and WIA drivers, which will let you scan directly from almost any Windows program that includes a scan command.
For most of my tests, I used the scan utility, which lets you define up to nine scan profiles, with settings for resolution, paper size, color mode, the format to save the file in, and more. You can also easily redefine the presets as needed, as well as store alternatives to the current settings for easy retrieval. Also very much worth mention is Visioneer's Acuity digital enhancement module, which is built into the utility, and lets you control settings like whether to straighten the image, automatically rotate pages to the right orientation, or drop out a given color to make the image more readable.
As with too many other scanners, the only way to pick a scan preset from the scanner's front panel is by number. However, the utility's pop-up screen on the computer shows enough information to make it easy to pick the right preset from the computer screen without having to memorize which number does what.
Performance The official speed rating for the 4830 is 30 pages per minute (ppm) for simplex (scanning one side) and 60 images per minute (ipm) for duplex (scanning both sides) at 200 pixels per inch (ppi) and black and white scan mode. In my tests using letter-size paper and scanning to image PDF format, however, I measured it at 25.0 ppm in simplex and 51.7 ipm in duplex. As with the Editors' Choice Kodak i2600 , which is rated at 100 ipm but came in at 76.9 ipm on our tests, that's a little short of the claimed speed, but within a reasonable range of the claim.
Because the text in the PDF image files looked a little ragged at 200 ppi, I also tried scanning at 300 ppi. As expected, the image quality improved considerably, with much more easily readable text. Even better, with simplex scans, the speed at 300 ppi was essentially the same as at 200 ppi. With duplex scans, however, the speed dropped considerably, to just 26.1 ipm. More precisely, the scan itself took about the same amount of time, but it took far longer to transfer the larger amount of data to the computer, which slowed down the total time for the scan.
Scanning to searchable PDF format, which is generally the more useful choice for document management applications, took relatively little extra time for the text recognition step. Using a 25-page document, I timed the scanner at 1 minute 44 seconds at 200 ppi and at 2:34 at 300 ppi. Scanning a single ledger-size page to searchable PDF format took 16 seconds for simplex mode and 19 seconds for duplex mode.
Text Recognition and Other Issues The scanner turned in a high score for OCR accuracy, reading both our Times New Roman and Arial test pages at sizes as small as 6 points without a mistake. It also did notably well with an assortment of other fonts that we don't usually report the performance for, because it's a given that few scanners can read them well. Most impressively, with two highly stylized fonts that most scanners fail to read without mistakes at any font size, the 4830 managed to read our test pages at sizes as small as 8 points without a mistake.
Unfortunately, I also ran into some issues that make the scanner a little less attractive than it could be. To begin with, the predefined settings in the scan utility don't include any for tabloid, ledger, or A3 paper sizes. The largest is for legal size. Another oversight is that some of the default definitions in the utility seemed designed for other scanners. In one case, the front and back of pages came out upside down relative to each other until I dug into the settings and set the utility to automatically rotate pages.
The good news is that these issues are more annoyances than serious problems. Once you get past them, by creating new scan definitions or modifying the default settings to match your needs, the scanner can do its job reasonably well.
Also worth mention is that for the setting issues I ran into there are at least two known fixes that Xerox is considering at this writing. The company says it should have decided on one and put it in place by the time you read this. Even without the fix, however, if you need to scan at tabloid or A3 size, and you need to scan multipage, duplex documents, the Xerox DocuMate 4830 is a more than reasonable choice and well worth a close look.
More Scanner Reviews: ??? Xerox DocuMate 4830 ??? Kodak ScanMate i940 ??? VuPoint Solutions Magic Wand PDS-ST441-VP ??? Ambir ImageScan Pro 940u ??? Ambir ImageScan Pro 930u ?? more
I was following one of those interesting Internet threads based on and around Elliot Mazer. For those of you that don't about producer, executive, technologist, and project leader (according to Wikipedia) Elliot Mazer, he has been in the music business for decades as a record producer for many classics including Neil Young's Harvest, Janis Joplin's Cheap Thrills, and the music for Martin Scorcese's Last Waltz to name just three very heavy hitters. Mazer also helped develop AirCheck, a system for monitoring when songs are played on the radio and TV, which was eventually sold to Radio Computing Services, Inc (RCS). Lately, he's been consulting to among others, Orastream which is where the string started for me.
If you recall, Orastream was involved in the high rez streaming service for Neil Young's newest Psychedelic Pill. I went from Mr. Mazer's Wikipedia page to Google which lead me to this interview in Sound On Sound and this nice quote:
"With 192kHz, the recording medium is not there, which is slightly different than when you use the best analogue system. The 192kHz format makes listening to digital pleasurable, and it does not sound digital. It moves me more. I feel the same about DSD [Sony's one-bit, super-high sample rate technology used in the Super Audio CD format] but 192/24 PCM is my favourite, and 192 sounds better than 96 by a long shot. I'll bet that 384 will sound even better. The differences are in the width, depth and height of the recording." ~ Elliot Mazer
There are interesting parallels to comments made by Barry Diament and Bruce Brown in their respective Audiostream Q&As. Here's Barry:
"When I first heard properly done 24/192, it was a jaw dropper. For the first time in my experience, those reservations I have always had about digital, where I felt there were some things the best analog did better, simply evaporated. This is, to my ears, a bigger jump up in quality over 24/96 than that was over 16/44. It no longer feels like a great digital recorder or a great analog recorder. It feels like the recorder has been effectively removed from the equation and I am listening directly to the mic feed." ~ Barry Diament
And Bruce Brown:
"To fully capture the nuances of tape, I feel the only way to do that is into either DSD64fs via a Grimm AD1 or to DSD128fs. That is the closest I?ve heard digital to master tape. That is how good tape can be. It trumps everything else." ~ Bruce Brown
Interesting, no?
Then I came across this interview with Mr. Mazer from Tape Op magazine which is where things take a turn for the worse:
Does the audiophile still exist today, or is this a dying breed? The audiophile breed is disappearing. They mostly don?t listen to music anyway - they listen to sound. There are a few record labels that specialize in that market. They produce ?high fidelity? recordings of music that sells equipment.
Ouch! I quickly ran to the nearest mirror and was relieved to see that I am not, in fact, disappearing (if anything, the opposite is true). What's more is when I add up all of these quotes, I have to wonder who Mr. Mazer thinks the audience for 192kHz and DSD recordings is/are? Hint: Audiophiles. And what's more is we are driving the market for HD download outlets like HDtracks, Qobuz, and Linn Records for remastered HD versions of classic records, not just "high fidelity" pap. Harumph!
I'd like to track down Mr. Mazer and see if I can interest him in a Q&A for AudioStream and also let him know that audiophiles come in all shapes and sizes and do not compress so neatly into such a small and unattractive package (but I admit that some audiophiles fit his description to a beefy-T).
I'd also like to thank him for such wonderful records and ask?What's up with Pono?
Part 4 in the series about buying a Los Angeles home is aimed at helping you gain an edge in the search process, especially in this sellers? market.
At this stage, you will have your financing in order in terms of knowing what you can afford and are willing to pay, you will have chosen your Los Angeles real estate agent,? and have sat down with them to determine your criteria. ?Now you are ready to go.
How does the search process work?
Your agent will send you listings from the Multiple Listing Service (MLS) which is the collection center for most of the homes on the market. ?This does not include homes sold by owners themselves ?(FSBOs) or pocket listings (homes that a seller does not want on the open market so the agent sells by word-of-mouth). ?Hopefully your agent will select only the ones that meet your criteria.
Time is of the essence in this market. ?Review the listings promptly and let your agent know which ones you would like to view and provide them with your availability.
Your agent will make appointments and you will start going out and seeing suitable properties.
When buying a Los Angeles home,?do not be afraid if the first one you see is the one you love. ?You do not have to see 20 more. ?It is human nature to think there might be something better. ?Most often there isn?t. ?And again, in this market time is of the essence. ?If you hesitate another buyer may snap it up.
If you are a first-time buyer making that first offer can be a nerve-wracking experience, but once you make your first offer you won?t look back.
You really do have to give up time in order to find the right house, but it only takes one.
Buying a Los Angeles Home ? The Series:
Step 1: ?Getting ready to buy
Step 2: ?Why use a Realtor?
Step 3: ?Define your criteria
Step 4: ?Start your search
Step 5: ?Make your offer?(about the purchase contract)
Step 6: ?Be prepared to negotiate
Step 7: ?Go through the escrow process
Step 8: ?The importance of a home inspection
What is not covered in a home inspection
Step 9: ?Prepare for your new home
Buying or Selling Los Angeles Real Estate
Buying or selling a Los Angeles home can be a daunting process in a city this size, especially if you?re new to L.A. You?ll need a resident expert to show you around and help you narrow down the areas where you might like to live. I will help you find the perfect home in the right area to fit your lifestyle, budget and needs!
When I list and sell Los Angeles homes for my clients I strive to make the experience a pleasant one. My mission is to provide outstanding service while utilizing the best practices and systems available.
If you are an absentee owner, you?ll need someone to handle all the details that you can?t handle remotely. That?s where I come in ? I?m there when you can?t be. I also specialize in lease property in Los Angeles.
Westside Los Angeles Real Estate, including, but not limited to:
For more information on how I can best serve your Los Angeles real estate needs, don?t hesitate to fill out the contact form or give me a call at 310-473-6919.
Jane Peters
I am a Los Angeles Realtor?, specializing in absentee owners, out-of-town-buyers and those needing that extra personal touch to make the buying and selling of Los Angeles real estate a smooth and, believe it or not, fun process.
? Local and national figures show that more people in their 50s and 60s are abusing illegal and prescription drugs, reports the Bradenton Herald. And, the problem appears especially prevalent in Florida.
While the use of illicit drugs remains relatively uncommon among people 65 and older, the number of illicit drug users 50 to 59 years old tripled between 2002 and 2011, from 900,000 to 2.7 million, according to the National Institutes of Health. The increase even prompted the NIH to post its first consumer alert on its website, NIHSeniorHealth.
More older adults are also seeking treatment for substance abuse. Drug-related hospitalizations and visits to emergency rooms were up 116 percent in the 55-to-64 age group from 2004 to 2010.
When asked if they had used an illicit drug in the past 30 days, boomers from 55 to 59 years old also posted the single largest increase of any age group in a single year. In 2010, 4.1 percent admitted to usage. By 2011, 6 percent did.
?That?s largely due to marijuana,? says Jim Hall, an epidemiologist for the Center on Applied Research on Substance Use and Health Disparities at Nova Southeastern University. ?These are people who began using it in the 1960s, when the use of marijuana escalated dramatically from 1966 to 1973, and they may never have quit.?
Though the actual number of midlife drug users is significantly lower in comparison to teenagers and twentysomethings, the alarming spike moved the NIH to urge physicians and family members to be alert for warning signs of drug abuse in older people.
?We don?t think of older adults as having a substance abuse problem,? says Dr. Gaya Dowling, chief of the science policy branch at the National Institute on Drug Abuse. ?We think of it as a young person?s problem.?
WORRISOME TREND
Statistics from Florida underscore the worrisome national trend of drug abuse among older adults. The percent of admissions to publicly funded treatment programs for patients 51 to 60 years old shot up 67 percent in the 10 years ending in 2011, according to data from the Florida Department of Children and Families.
Today?s fiftysomething Floridians are also more likely than other generations to be addicted to both alcohol and illicit drugs. In 2001, 3.6 percent of those entering treatments for dual addictions were 51 to 60 years old. By 2011, that had shot up to 14 percent.
This column highlights the most interesting and useful business and financial commentary on consumer companies from around the Web.
Examiner Link: Best Cyber Monday 2012 Tech Deals: Wal-Mart, Amazon, Gamestop, Target, and Best Buy (Video)
?Sunday,?Wal-Mart (NYSE:WMT), Target (NYSE:TGT), Amazon (NASDAQ:AMZN), and Best Buy?(NYSE:BBY) emailed customers about their exciting Cyber Monday sales and adding products to their sale list; Black Friday weekend is the biggest shopping weekend of the year and Cyber Monday...is the online version of Black Friday. Sunday, Amazon, Wal-Mart, and Target started their Cyber Monday deals and are calling them Cyber Week deals.
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?Wal-Mart has hundreds of items on sale for Cyber Week including: a 32? JVC TV for $199, an iPod Touch bundle kit from $179, Power Wheels Barbie Jeep from $88, and more. For more information on?Wal-Mart?s Cyber Week sales,?click here.?
? Reuters Link: US Holiday Shoppers Buy Early, Often, Online
?US shoppers went to stores earlier this Thanksgiving weekend and bought online more than in years past, giving retailers a strong start to the holiday shopping season, data showed on Sunday.
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?The more successful retailers, analysts said, were companies such as Wal-Mart Stores Inc and Macy's Inc (NYSE:M), which did better at combining physical stores with their online and mobile channels into a seamless shopping experience.?
? Tech Crunch Link: Pushing Fire Sales Outside the US, Amazon Says UK Black Friday Kindle Device Sales Tripled Previous Record, Stays Mum on Hard?Numbers
?Black Friday is not just for Thanksgiving-celebrating Americans. Amazon today?announced?that in the UK, where it has also been running Black Friday sales, it sold a record number of Kindle devices ? triple the previous record amount. As usual with Amazon, it is not giving a hard figure on how many actual units this means, or how many e-readers it sold compared to Fire tablets.
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?But it looks like at least some of the focus of activity here ? at least as Amazon would like it to be seen ? is on its Kindle Fire tablet.?
? Tucson Citizen Link: Scattered Wal-Mart Protests Don?t Dent Bottom Line
?Scattered?walk-outs and protests by Wal-Mart workers and their supporters?in at least nine states may have scored symbolic points Friday by taking on the retail giant head-on, but apparently they did little to keep shoppers away as the company quickly claimed its best Black Friday ever.
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?The company said in a?statement?Friday morning that its stores rang up almost 10 million transactions from the time doors opened for Black Friday shoppers at 8 p.m. Thursday until midnight, or about 5,000 items per second.?
? Dividend.com Link: Janney Commented on Black Friday and Holiday Sales on Apparel and Footwear Companies
?On Monday analysts at Janney reported on Black Friday traffic and sales which could lead to positive Holiday sales expectations for companies like Foot Locker Inc.?(NYSE:FL), Finish Line Inc.?(NASDAQ:FINL), and Dicks Sporting Goods Inc. (NYSE:DKS).
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?Overall, analyst Eric Tracy said that traffic on Black Friday was lighter than in years past, but this could be due to a migration to online shopping as well as extending hours at various malls and retail stores.?
? HiDownload Platinum 8.0.1 | 4.6 MB HiDownload is a multi-threaded download manager that allows you to download individual files (or lists of files) from web and FTP sites while maximizing the potential of your internet connection. It also supports multimedia streaming and and RTSP (Real Time Streaming Protocol) with optional resume, enabling you to download movies, music and capture streaming video and audio,record radio from Internet. HiDownload also offers a built-in Broadcast Manager. In addition, it provides all the standard features of a download manager, including scheduling, drop basket, download history, clipboard monitoring, download categories as well as zip preview and more. Main Features: * Accelerated Downloads:By splitting the files into several parts and downloading them at the same time you save time. * Support HTTP,FTP,RTMP, MMS/MMST/MMSU,RTSP,PNM protocols * Support rapidshare, megaupload and other similar sites(Premium Account) * Record Streaming Video and Streaming Audio * All the popular streaming formats are supported, including: o Windows Media o Real Audio and Real Video o QuickTime o Flash Video (FLV) o Streaming MP3 (Shoutcast) * Record all kinds of great online media, including: o Music Videos. o YouTube, PutFile, Google Video and other Video Sites. o Live Internet TV and Radio. o Shoutcast and other Streaming MP3 radio. * Support Meta-files: ram, smil, asx, wax, wvx, m3u, pls, ? * Categories:you can easily have files of certain types downloaded automatically to a folder you specify * Live Broadcast Manager * Build-in Podcast Manager, schedule to download podcast * Browser Integratio * Advanced Scheduler:you decide when and what will be downloaded * Zip Preview:view the contents of Zip files before download * Zip Extract:download & extract specific files from zip archive * Virus Checking:You may select files that have been downloaded and scan them. * Support Proxy Server:You may set HiDownload to use a proxy server according to your network configuration. * Cookies support * Rename automatically
Download : link
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I must change the windows of my home. My old windows aren't bad looking. But although they go well with the house and I still like them, they are lacking the much needed energy efficiency. Heating and cooling my home takes five times longer than it is supposed to. I talked to the contractor that I always use, and after inspecting them, he told me that is time for windows upgrade. Because I really like the window design I have, I went in search for the similar window style only with a better energy efficiency index. I found something that looks promising at the Nitro Windows store my next door neighbor suggested. I?ll see soon enough how they will do.?
When the?3-D version of "The Hobbit: An Unexpected Journey" debuts in movie theaters on Dec.?14, the film will likely wow viewers with its special effects. But audiences at select theaters will get even more bang for their buck: they?ll be the first to witness a new technology that displays images at a rate of 48 frames per second, twice as fast as the current standard.
The new display rate is sure to look different. Whether audiences will like it is less certain. So far, early reviews have been mixed, according to 3D Focus, a website that tracks changes in 3-D-viewing technology.?
BLOG: Is 3-D vision bad for you??
Some people think the effects look "too real." For others, eyestrain, headaches, nausea and other discomforts are as much of a hazard as they were with the older technologies. That's because most films that are designed to make images look like they are popping out of the screen work by showing each eye different pictures at different times. That forces the brain to merge conflicting messages -- an obstacle that 3-D studios are still working to overcome.
"People really differ," said Marty Banks, a vision scientist at the University of California, Berkeley. "Some people just don't get it and they're fine. Other people are fairly uncomfortable. The industry is really worried about this. They're listening to us?scientists and they?re taking our advice."
ll movies, whether "2-D" or "3-D" create the illusion of movement by flashing one still image after another onto the screen at a rate that is fast enough to fool our brains into seeing action. If the sequence of images is presented too slowly, the result is a shaky effect called "judder" that can sometimes look like a double image.
3-D technology (which Banks prefers to call stereo-3-D or S3-D because even "2-D" movies look three-dimensional) raises the risk for judder because these films usually show screen shots in an alternating sequence to one eye at a time. First the left eye sees an image, then the right eye sees one, then the left eye sees the next image, and so on.
With the latest generation of 3-D glasses, polarizing filters allow each eye to see light coming from just one direction, and screen shots are displayed so that a single lens is targeted at a time. When one eye is stimulated, the other eye is presented with darkness.
It's up to the brain to put everything together into a coherent picture. But with each eye seeing alternating flashes of brightness and darkness, jumpy judder can creep in, causing distraction or discomfort.
BLOG: Sony?s 3-D digital recording binoculars
To solve that problem, 3-D films that are shot at a standard 24 frames per second actually show the left eye a single image three times in a row with flashes of darkness in between. Then the right eye gets its image three times in a row, and that pattern continues for the entire film. This "triple flashing" allows the screen to display 72 frames per second, which reduces flicker effects.
For the new Hobbit, director Peter Jackson used new technology to film at 48 frames per second instead of 24. In real life, our visual systems take in information continuously, and some experts speculate that images will need to be captured at more than 100 or even 150 frames per second before a movie looks truly real. But with any increase in frame-rate speed, motion should look smoother and more realistic.
"As you increase the rate of new incoming data, you're getting closer and closer to the real world," Banks said. "At some rate, you will get to the point where you can?t tell the difference."
But first, moviemakers have some technical issues to deal with.
One question, Engle said, is whether the technological limitations of the projectors used by most theaters will require them to use fewer flashes for each eye before switching to the other eye?s image????a switch that could actually cause new stuttering problems.
NEWS: Underwater movie maker: Shaun MacGillivray
Some theaters use a dual-projector set-up that gets around that issue by showing images to both eyes at the same time, and in those cases, Engle said, the results should be spectacular. But theaters that use a single projector to display 3-D movies will have some new decisions to make, and audiences might not be universally happy about the final product.
"You have to be careful what you wish for," said Rob Engle, 3-D supervisor at a major film studio in Burbank, Calif. "If you have to make compromises in order to increase the frame rate by decreasing the flash rate, you start to run into trade-offs."
As higher frame rates lead to more realism, dismay is also cropping up among people who are used to seeing films that look like films rather than television or real life. Similar complaints have emerged whenever filmmaking technology has risen to a new level over the decades.
"Every time we've moved closer to reality by adding sound, adding color or getting rid of scratches, in the end, the audience has accepted it and there's no going back," Banks said. "I think the same is going to be true here.
"In the end, we all want immersion. We want to feel like we're in that scene and closer to reality. I think once people see it, they are going to go, 'Wow. I want that.'"
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After the success of Louis CK's direct-to-fan specials, video startup Chill is pivoting -- again -- and coming out with a new product that it hopes will provide a new channel for independent content creators to sell their videos in the same fashion.![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 29-Nov-2012
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While the use of illicit drugs remains relatively uncommon among people 65 and older, the number of illicit drug users 50 to 59 years old tripled between 2002 and 2011, from 900,000 to 2.7 million, according to the National Institutes of Health. The increase even prompted the NIH to post its first consumer alert on its website, NIHSeniorHealth.
